GTN spray

Information for patients from Medicines Information

Your doctor has prescribed you GTN spray. This leaflet explains how to use and care for your spray.  

Please use these instructions alongside advice from your doctor, pharmacist, or specialist nurse.

What is GTN spray?

Glycerol Trinitrate or GTN spray belongs to a group of medicines called nitrates. It widens the blood vessels, which increases blood flow to the heart.

What is GTN spray used for?

GTN spray relieves chest pain and discomfort from angina at the onset of an angina attack. Angina is a heart condition caused by restricted blood flow to the heart.

How do I use GTN spray? 

  1. Before you use the spray for the first time

    • Prime the pump by releasing a test spray.

    • If you do not use the spray regularly, repeat the test spray each time to make sure the pump is working properly. 

  2. Using the spray

    • Sit down and stay calm. This will reduce the stress on your heart and minimize your risk of feeling faint.

    • Do not use the spray near heat, an open flame, or while smoking.

    • Remove the plastic cap from the spray. Do not shake the container.

    • Hold the pump upright and near your mouth, with your forefinger on the top of the grooved button.

    • Aim the spray under your tongue.

    • Press the button firmly with your forefinger to release the spray 1 to 2 times. Try not to inhale the spray.

    • Close your mouth immediately after spraying. Do not spit out the spray or rinse your mouth for 5 to 10 minutes.

  3. How will I feel afterwards?

    • You may feel a warm tingling sensation, which is normal.

    • Within a few minutes you should feel relief from your chest pain or discomfort.

  4. What if my pain continues after using the spray?

    • If you still have pain or discomfort after 3 to 5 minutes, repeat the process with another 1 to 2 sprays.

    • Call 999 immediately, if:

      • you do not experience pain relief within a few minutes of taking the second dose; or

      • your pain gets worse.

  5. What should I do after using the spray?

    • Rest for a moment.

    • When you stand up, do so slowly to avoid feeling faint or dizzy.

Can I use GTN spray to prevent an attack?

If you know what brings on your angina, you can use GTN spray to prevent an attack. However, if you find that you are frequently using your spray, this may mean your condition is getting worse. If this happens, please have your prescription reviewed by your doctor.

What are the possible side effects?

The most common side effect is a headache, this should soon pass.

Important things to remember

How do I store my GTN spray?

Additional information

For more information on using your GTN spray, please watch the following YouTube video GTN spray for angina counselling.